Today, I upgraded to Wordpress 2.5. The upgrade proces was easy as usual. Before the upgrade I checked all the plugins used, and upgraded those first. The new features / layout of the adminpages are great. Also the new editor works like a charm (even on Safari). Somehow it feels a bit more intuitive.
Only downside is that the Wordpress Stats on the dashboard won't work in FireFox. It works fine in Safari. Instead of showing the graph in FireFox it shows the actual dasboard page from wordpress.com.